Friday, July 26, 2024

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ScienceDaily: All - July 26, 2024

Today's top research news

 
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Folded peptides are more electrically conductive than unfolded peptides

What puts the electronic pep in peptides? A folded structure, according to a new study. Researchers combined single-molecule experiments, molecular dynamics simulations and quantum mechanics to validate the findings.


New drug shows promise in clearing HIV from brain

An experimental drug originally developed to treat cancer may help clear HIV from infected cells in the brain, according to a new study. By targeting infected cells in the brain, drug may clear virus from hidden areas that have been a major challenge in HIV treatment.


'Kink state' control may provide pathway to quantum electronics

The key to developing quantum electronics may have a few kinks. According to researchers, that's not a bad thing when it comes to the precise control needed to fabricate and operate such devices, including advanced sensors and lasers. The researchers fabricated a switch to turn on and off the presence of kink states, which are electrical conduction pathways at the edge of semiconducting materials.

Image: Calin-H/Shutterstock.com


New research in fatty liver disease aims to help with early intervention

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis. MASH is a consequence of poor diet and obesity and results in severe damage to the liver. In MASH, the liver becomes filled with active and rapidly multiplying T cells, which are a type of immune cell. In today's study researchers examine what these T cells look like and how they work in people with liver cirrhosis (a late stage of liver disease) and in an animal model of MASH.


Chemical analyses find hidden elements from renaissance astronomer Tycho Brahe's alchemy laboratory

Danish Tycho Brahe was most famous for his contributions to astronomy. However, he also had a well-equipped alchemical laboratory where he produced secret medicines for Europe's elite.


Nitrogen emissions have a net cooling effect: But researchers warn against a climate solution

An international team of researchers has found that nitrogen emissions from fertilizers and fossil fuels have a net cooling effect on the climate. But they warn increasing atmospheric nitrogen has further damaging effects on the environment, calling for an urgent reduction in greenhouse gas emissions to halt global warming.


New Zealand's flightless birds are retreating to moa refuges

Researchers have found New Zealand's endangered flightless birds are seeking refuge in the locations where six species of moa last lived before going extinct.


Indoor solar cells that maximize the use of light energy

Chemists have synthesized materials that can improve solar elements for indoor use. Such photovoltaic cells, which can also be integrated into various electronic devices, generate electricity even in low-light conditions.


How molecular interactions make it possible to overcome the energy barrier

Non-reciprocal interactions allow the design of more efficient molecular systems. Scientists now propose a mechanism on how energy barriers in complex systems can be overcome. These findings can help to engineer molecular machines and to understand the self-organization of active matter.


Quantum sensor for the atomic world

In a scientific breakthrough, an international research team has developed a quantum sensor capable of detecting minute magnetic fields at the atomic length scale. This pioneering work realizes a long-held dream of scientists: an MRI-like tool for quantum materials.


Physical training improves quality of life in advanced breast cancer

Targeted physical training can improve the quality of life of patients with metastatic breast cancer and alleviate fatigue. This is shown by an international randomized multicenter study. In the course of the training program, which included two sessions per week over nine months, disease- and therapy-related symptoms were markedly reduced, which was associated with a improved quality of life compared to the control group.


Size doesn't matter for mammals with more complex brains

Mammals that have evolved more developed brains tend to have a smaller size difference between males and females of that species, according to new research.


Warming has more impact than cooling on Greenland's 'firn'

A new study finds disproportionate effects of temperature shifts on an icy glacier layer.


Sodium channels in breast cancer cells a promising target for future treatments, study reveals

A new study adds to evidence which suggests treating breast cancer patients with sodium channel blockers could be a promising future treatment to prevent the spread of cancer during the gap between diagnosis and surgery.


Solar absorption by black carbon in fire clouds quantified

Aerosol scientists quantify the extent of light absorption by black carbon in fire clouds to better model climate impacts of extreme wildfire events.


Artificial blood vessels could improve heart bypass outcomes

3D-printed blood vessels, which closely mimic the properties of human veins, could transform the treatment of cardiovascular diseases. Strong, flexible, gel-like tubes -- created using a novel 3D printing technology -- could improve outcomes for heart bypass patients by replacing the human and synthetic veins currently used in surgery to re-route blood flow, experts say.


Scientists identify key protein behind spread of shingles virus

Scientists have discovered a new evasion strategy used by the varicella zoster virus, which causes chickenpox and shingles, that may allow it to affect tissues far from the original site of infection.


Method enables fast, accurate estimates of cardiovascular state to inform blood pressure management

A new mathematical method, validated with experimental animal data, provides a fast, reliable and minimally invasive way of determining how to treat critical blood pressure changes during surgery or intensive care.


Space-trekking muscle tests drugs for microgravity-induced muscle impairment

A gentle rumble ran under a researcher's feet as a rocket carrying her research -- live, human muscle cells grown on scaffolds fixed on tiny chips -- lifted off, climbed, and disappeared into the sky to the International Space Station National Laboratory. These chips would help her better understand muscle impairment, often seen in astronauts and older adults, and test drugs to counter the condition.


In clinical trial, fecal matter transplant helped half of patients with gastrointestinal cancers overcome resistance to immunotherapy treatment

Findings from a small, proof-of-concept clinical trial have suggested that fecal microbiota transplants (FMTs) can boost the effectiveness of immunotherapy in a range of gastrointestinal cancers. In the study, six of 13 patients who had previously shown resistance to immune checkpoint inhibitors benefited from receiving FMTs from donors who had previously responded to treatment. The investigators also identified specific strains of bacteria associated with better or worse responses to FMT and immune checkpoint drugs.


Great Salt Lake a significant source of greenhouse gas emissions

Newly announced research examining greenhouse gas emissions from the drying lake bed of Great Salt Lake, Utah, calculates that 4.1 million tons of carbon dioxide and other greenhouse gases were released in 2020. This research suggests that drying lake beds are an overlooked but potentially significant source of greenhouse gases, which may further increase due to climate change.


A recipe for zero-emissions fuel: Soda cans, seawater, and caffeine

Engineers discovered that when the aluminum in soda cans is purified and mixed with seawater, the solution produces hydrogen -- which can power an engine or fuel cell without generating carbon emissions. The reaction can be sped up by adding caffeine.


Study suggests preoperative iron infusions work better than blood transfusions for some anemic patients

In a rigorous medical records study covering tens of thousands of patients, researchers conclude that some patients with preoperative anemia have better outcomes if they get iron infusions before surgery rather than standard red blood cell transfusions.


Engineer develops technique that enhances thermal imaging and infrared thermography for police, medical, military use

A new method to measure the continuous spectrum of light is set to improve thermal imaging and infrared thermography.


Scientists study how to bring you 'climate-smart coffee'

Coffee beans consumed across the globe come from two species: Coffea arabica and Coffea canephora. By 2050, about 80% of Arabica production is predicted to decrease because of climate change. Researchers are investigating to see if they can find alternative coffee cultivars.


New study shows at-home colon cancer screening test reduces risk of colorectal cancer death, as effective as screening colonoscopy

A noninvasive colorectal cancer screening test that can be done at home could reduce the risk of colorectal cancer death by 33%, according to a new study.


Next-gen cooling system to help data centers become more energy efficient

Artificial intelligence (AI) is hot right now. Also hot: the data centers that power the technology. And keeping those centers cool requires a tremendous amount of energy. The problem is only going to grow as high-powered AI-based computers and devices become commonplace. That's why researchers are devising a new type of cooling system that promises to dramatically reduce energy demands.


Electrical currents may make body's cancer-killing cells even better killers

Scientists have discovered that electrical currents may make Natural Killer (NK) cells -- our very own cancer-killing immune cells -- even better killers, which could have significant implications for treating some cancers. The scientists found that Tumour Treating Fields (TTF) in the laboratory (which mimic exposure of brain tumors to electric currents via a simple hat worn by patients) evoked an even more deadly response from NK cells. They hope their promising findings may open the door to new combined therapies for people living with certain brain tumors, such as glioblastoma.


Better way to produce green hydrogen

Researchers have developed a material that shows a remarkable ability to convert sunlight and water into clean energy.


Raindrops grow with turbulence in clouds

Tackling a long-time mystery, scientists have found that the turbulent movements of air in clouds play a key role in the growth of water droplets and the initiation of rain. The research can improve computer model simulations of weather and climate and ultimately lead to better forecasts.


How a bacterium supports healing of chronic diabetic wounds

New research shows that a certain bug, Alcaligenes faecalis (A. faecalis), can facilitate healing of hard-to-treat wounds among people with diabetes. While there are many studies done on potentially harmful bacteria in wounds, the researchers discovered that A. faecalis, a bacterium found in many types of chronic wounds, actually boosts healing of diabetic wounds. The researchers found that the beneficial bacterium can promote skin cell movements that are essential for wound closure by inhibiting enzymes that are over-produced in people with diabetes.


Array pinpoints imprinted genes with potential links to disease

Researchers from North Carolina State University have developed an array that assesses methylation levels of genes located in imprint control regions (ICRs) within the human genome. The array represents a cost-effective, efficient method for exploring potential links between environmental exposures and epigenetic dysregulation during the early developmental origins of diseases and behavioral disorders.


How evolution tamed a deadly virus and why we should still worry

Over the last century, a once-deadly mosquito-borne virus has evolved so that it no longer sickens humans. New research shows that changes in the virus's ability to target human cells paralleled the decline in illness and death. The findings offer important lessons in virology that may help guide better preparedness for future outbreaks of other viral diseases.


Tackling industrial emissions begins at the chemical reaction

Researchers are proposing a new way to curb industrial emissions, by tapping into the 'atomic intelligence' of liquid metals to deliver greener and more sustainable chemical reactions.


Parched Central Valley farms depend on Sierras for groundwater

New research shows California's Central Valley, known as America's breadbasket, gets as much as half of its groundwater from the Sierra Nevadas. This is significant for a farming region that, in some parts, relies almost entirely on groundwater for irrigation.


Spin qubits go trampolining

Researchers have developed somersaulting spin qubits for universal quantum logic. This achievement may enable efficient control of large semiconductor qubit arrays. The research group recently published their demonstration of hopping spins and somersaulting spins.


New gene therapy approach shows promise for Duchenne muscular dystrophy

Researchers have made a significant breakthrough in developing a new gene therapy approach that restores full-length dystrophin protein, which could lead to new treatments for people with Duchenne muscular dystrophy (DMD).

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