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"Molecular zip code draws killer T cells straight to brain tumors."

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Russ Roberts (https://hawaiisciencejournal.blogspot.com).

 

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18

Today

Molecular zip code draws killer T cells straight to brain tumors

Engineered immune cells target inflammation

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ScienceDaily / 42min

Scientists have developed a 'molecular GPS' to guide immune cells into the brain and kill tumors without harming healthy tissue.

Rapid surge in global warming mainly due to reduced planetary albedo

Global warming spike linked albedo

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ScienceDaily / 42min

Rising sea levels, melting glaciers, heatwaves at sea -- 2023 set a number of alarming new records. The global mean temperature also rose to nearly 1.5 degrees above the preindustrial level, another record. Seeking to identify the causes of this sudden rise has proven a challenge for researchers. After all, factoring in the effects of anthropogenic influences like the accumulation of greenhouse ga

Mangroves save $855 billion in flood protection globally, new study shows

ScienceDaily / 42min

Mangroves have been shown to provide $855 billion in flood protection services worldwide, according to a new study.

Shaking sensor continuously monitors inflammation

Implantable sensors track inflammation

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ScienceDaily / 42min

First-of-its-kind sensor monitors fluctuating proteins within the body in real time. In an animal study, device accurately tracked biomarkers of inflammation. Device also could track protein markers for other illnesses, including heart failure.

Scientists discover new receptor for nerve growth factor--a promising target for treating pain

New receptor discovered for pain treatment

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ScienceDaily / 42min

Researchers have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according to a new study. The findings hold promise for finding new treatments for arthritis and other forms of inflammatory and cancer pain, without the side effects that led recent therapies to fail in clinical trials.

New drug tested to reduce side effect of 'half-matched' stem cell transplants

ScienceDaily / 42min

Stem cell transplantation is used to treat several types of blood cancers, but carries the risk of a life-threatening side effect called graft-versus-host disease. Results from a clinical trial showed adding the investigational drug itacitinib to standard care for 'half-matched' stem cell transplantation may reduce rates of the disease, in which the donor's stem cells attack the patient's healthy

From one gene switch, many possible outcomes

ScienceDaily / 42min

Scientists have uncovered surprising ways transcription factors, the genetic switches for genes, regulate plant development. Their findings reveal how subtle changes in a lipid-binding region called the START domain can dramatically alter gene regulation, paving the way for advancements in crop engineering, synthetic biology, and precision gene therapies.

Innovative immunotherapy shows promise in early clinical trial for breast cancer

Novel immunotherapy shows promise

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ScienceDaily / 42min

A groundbreaking phase one clinical trial explored a novel cell-based immunotherapy for breast cancer. The study focuses on a new treatment approach that aims to harness the body's immune system to enhance patient responses and reduce the need for conventional chemotherapy and its associated toxicities. The trial involved 12 patients with locally advanced stage I-III HER2 breast cancer.

Particle research gets closer to answering why we're here

ScienceDaily / 42min

Physicists have outlined the next 10 years of global research into the behavior of neutrinos, particles so tiny that they pass through virtually everything by the trillions every second at nearly the speed of light.

That's no straw: Hummingbirds evolved surprisingly flexible bills to help them drink nectar

ScienceDaily / 42min

Hummingbird bills -- their long, thin beaks -- look a little like drinking straws. But new research shows just how little water, or nectar, that comparison holds. Scientists have discovered that the hummingbird bill is surprisingly flexible. While drinking, a hummingbird rapidly opens and shuts different parts of its bill simultaneously, engaging in an intricate and highly coordinated dance with i

Climate change threatens global food supply: Scientists call for urgent action

Gene editing essential for food security

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ScienceDaily / 42min

As climate change accelerates, scientists are sounding the alarm about its potentially devastating impact on the world's food supply. Researchers warn that without rapid changes to how we develop climate-resilient crops, we could face widespread food shortages leading to famine, mass migration, and global instability.

Analyzing multiple mammograms improves breast cancer risk prediction

AI improves breast cancer risk prediction

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ScienceDaily / 42min

A new method of analyzing mammograms identified individuals at high risk of developing breast cancer more accurately than the standard, questionnaire-based method did. The new method, powered by artificial intelligence, could help diagnose cancer earlier and guide recommendations for earlier screening, additional imaging or risk-reducing medications.

Changes in blood cell production over the lifetime could impact leukemia outcomes

ScienceDaily / 42min

The first comprehensive map of the dramatic changes that take place in the blood system over the course of the human lifetime could have implications for the treatment of acute myeloid leukemia and other blood diseases.

Controlling cancer cells' gluttony for glutamine

Cancer cells exploit glutamine resources

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ScienceDaily / 42min

Researchers describe two enzymes newly identified for their roles in regulating macropinocytosis, a process cancer cells use to snatch extra nutrients from the jelly-like substance between cells. This allows tumors to fuel their growth even when they consume more energy and other resources than they can acquire from nearby blood vessels.

Unlocking the science of sleep: How rest enhances language learning

Sleep enhances language learning

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ScienceDaily / 42min

Sleep is critical for all sorts of reasons, but a team of international scientists has discovered a new incentive for getting eight hours of sleep every night: it helps the brain to store and learn a new language.

Spotted lanternflies in the US are living longer--and cities may be helping them spread

ScienceDaily / 42min

Spotted lanternflies -- invasive insects that first landed in the United States a decade ago -- are emerging earlier and staying active later each year, according to an analysis of citizen-science data by researchers. This longer life cycle and shift in activity may be driven in part by cities and their warmer climates.

New research measures vibrations that make city bus rides uncomfortable

ScienceDaily / 42min

To improve the riding experience and safety, the research team has identified several potential enhancements, including better suspension systems, redesigned seats to absorb vibrations more effectively, and driver monitoring systems to encourage smoother driving practices.

New research on chronic inflammation explores potential treatments for chronic diseases and cancer

Chronic inflammation linked to cancer

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ScienceDaily / 42min

A recently published study on a new approach to understanding chronic inflammation could lead to new advancements in the treatment of many debilitating medical conditions, including cancer.

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